Synopsis

Alcohol consumption during pregnancy and health and development of index child at birth and 12-24 months of age.

Summary

Study name Asking Questions about Alcohol in Pregnancy Study
Study abbreviation AQUA
Current principal investigator/s Prof Jane Halliday NHMRC Senior Research Fellow, Public Health Genetics, Murdoch Childrens Research Institute (MCRI), Melbourne
Dr Colleen O’Leary NHMRC Postdoctoral Research Fellow, National Drug Research Institute, Curtin University, Perth
Prof Della Forster Research Fellow, Mother and Child Health Research, La Trobe University, Melbourne
A/Prof Susan Donath Research Fellow, Clinical Epidemiology & Biostatistics Unit, MCRI
A/Prof Peter Anderson NHMRC Senior Research Fellow, Vic. Infant Brain Studies (VIBeS), MCRI, Melbourne
Dr Sharon Lewis Senior Research Officer, Public Health Genetics, MCRI, Melbourne
Prof Elizabeth Elliott Consultant Paediatrician, The Children’s Hospital at Westmead, Sydney
Dr Cate Nagle Senior Lecturer, Faculty of Health, Medicine, Nursing & Behaviour, Deakin Univ., Geelong
Dr Jeffrey Craig Group Leader, Developmental Epigenetics, MCRI, Melbourne
Evelyne Muggli Senior Research Officer, Public Health Genetics, MCRI, Melbourne 
Current project manager Evelyne Muggli
Cohort representative (study contact) Prof Jane Halliday 
Postal address AQUA study, Murdoch Childrens Research Institute, Reply Paid 907, Parkville VIC 3052
Phone +613 83416260 
Email

evi.muggli@mcri.edu.au

aquastudy@mcri.edu.au

Primary Institution Murdoch Childrens Research Institute 
Collaborating Institution/s National Drug Research Institute, Curtin University, Perth; La Trobe University, Melbourne; The Children’s Hospital at Westmead, Sydney; Deakin University, Geelong. Project Partner Maternity Hospitals: Mercy Hospital for Women; Royal Women’s Hospital; Monash Medical Centre; Casey Hospital; Dandenong Hospital; Box Hill Hospital
Major funding sources NHMRC; VicHealth; McCusker Charitable Foundation; Brockhoff Foundation; Financial Markets for Children
Study website https://www.mcri.edu.au/research/projects/asking-questions-about-alcohol-pregnancy-aqua/
Key reference Muggli, E., O’Leary, C., Forster, D., Anderson, P., Lewis, S., Nagle, C., Craig, J.M., Donath, S., Elliott, E. and Halliday, J. (2014). Study protocol: Asking QUestions about Alcohol in pregnancy (AQUA): a longitudinal cohort study of fetal effects of low to moderate alcohol exposure. BMC Pregnancy Childbirth, 14: 302. doi: 10.1186/1471-2393-14-302
Are data available outside study team? Not at present
Study focus Alcohol consumption during pregnancy and health and development of index child at birth and 12-24 months of age
Sampling frame Women attending one of seven antenatal clinics in metropolitan Melbourne in 2011-12 who are < 19 weeks pregnant with single baby
Year commenced 2011
Commencement sample 2146
Intergenerational? No 
Imaging Optional maternal and infant cheek swab, blood, placenta 
Linkage 3D photo of face at 12 months
Biosamples? Electronic hospital medical records (through maternal UR numbers)

Waves

Wave Year Age (mean, range) Eligible sample
1  2011-2012  < 19 weeks gestation 2146
2 2011-2012 26 weeks gestation 1715
3 2011-2012 36 weeks gestation 1571
4 2013-2014 12 months old (includes birth) 1566 eligible (not withdrawn), 1296 completed survey. 518 completed 3D anthropometric mask sub-study.
5 2014-2015 2 years 1519 eligible (not withdrawn), 1038 completed survey. 564 completed developmental assessment sub-study.