Synopsis
The ORIGINS Project is a longitudinal birth cohort study, designed to collect detailed information about how early environment influences the risk of a broad range of non-communicable diseases, including asthma, allergies, diabetes, obesity and its many complications. We recruit pregnant women and their partner early in pregnancy and data is collected on their health, diet, physical activity patterns and a range of factors in their environment. These early life exposures will be assessed on how they influence the children’s growth, development, and health (including neurodevelopment, evidence of allergies, infections, and other medical history). Children are followed up until they turn 5 years of age. ‘Active’ participants are followed up at numerous timepoints, and ‘non-active’ participants provide access to routinely collected hospital data.
Summary
Study name |
The ORIGINS Project |
Study abbreviation |
ORIGINS |
Current principal investigator/s |
Susan Prescott and Desiree Silva |
Phone |
+61 8 9408 3118 |
Email |
ORIGINSProject@telethonkids.org.au |
Primary Institution |
Telethon Kids Institute |
Major funding sources |
Ramsay Health Care, NHMRC Project grant, Telethon Perth Children’s Hospital Research Fund (2), Telethon Kids Institute, WA DoH Merit Fellowship |
Study website |
originsproject.telethonkids.org.au |
Study focus |
To create a platform based upon a large databank and biobank for clinical intervention trials, nested studies, data analyses, etc. Each sub-study will require separate approval from the ORIGINS Scientific Committee and Biobank Governance Committee and then from the JHC HREC |
Sampling frame |
Families intending to deliver at the Joondalup Health Campus (public and private), Western Australia |
Year commenced |
2016 |
Commencement sample |
TBC |
Intergenerational? |
Yes |
Imaging |
Yes |
Linkage |
Yes |
Biosamples? |
Yes |
Waves
Wave |
Year |
Age (mean, range) |
Eligible sample |
Pregnancy |
2017 – 2023 |
10-24 wks, 36 wks |
Active participants: Finished recruitment |
Pregnancy |
2017 – 2027 |
10-24 wks, 36 wks |
Non-active participants: Currently recruiting |
Infancy & Childhood |
2017 – 2027 |
Birth, 2m, 6m, 1y, 3y, 5y. |
Currently following-up |