Synopsis

The ORIGINS Project is a new longitudinal birth cohort study, designed to collect detailed information about how early environment influences the risk of a broad range of non-communicable diseases, including asthma, allergies, diabetes, obesity and its many complications. Women (and the father of their baby) will be recruited early in pregnancy and data will be collected on their health, diet, physical activity patterns and a range of factors in their environment. These early life exposures will be assessed on how they influence the children’s growth, development, and health (including neurodevelopment, evidence of allergies, infections, and other medical history).

Summary

Study name  The ORIGINS Project
Study abbreviation ORIGINS
Current principal investigator/s  Susan Prescott, Desiree Silva and Lyn Colvin
Phone  +61 8 9408 3118
Email  ORIGINSProject@telethonkids.org.au
Primary Institution  Telethon Kids Institute
Major funding sources  Ramsay Health Care, NHMRC Project grant, Telethon Perth Children’s Hospital Research Fund (2), Telethon Kids Institute, WA DoH Merit Fellowship
Study website  https://originsproject.telethonkids.org.au/
Study focus  To create a platform based upon a large databank and biobank for clinical intervention trials, nested studies, data analyses, etc. Each sub-study will require separate approval from the ORIGINS Scientific Committee and Biobank Governance Committee and then from the JHC HREC
Sampling frame  Families intending to deliver at the Joondalup Health Campus (public and private), Western Australia
Year commenced  2016
Commencement sample TBC
Intergenerational? Yes
Imaging Yes 
Linkage Yes 
Biosamples? Yes 

Waves

Wave Year Age (mean, range) Eligible sample
1 Pregnancy 2016 – 2020 18, 28, 36 weeks  Currently recruiting
2 Infancy & Childhood 2016 – 2025 2,4,6,9,12,18 months, 2,2½,3,4,5 years  TBD