Synopsis

The Triple B Study: Bumps, Babies and Beyond is an innovative Australian study of approximately 1600 families. The project is a longitudinal pregnancy cohort which examines a wide range of biopsychosocial factors that relate to the health and development of Australian children and families. Importantly, the project has a key focus on examining the impacts of alcohol, tobacco and other drug use in pregnant women and their partners during the prenatal period on infant development and family functioning. The results of this study will inform public health and treatment initiatives that improve the health and well-being of Australian children and families. 

Summary

Study name The Triple B Pregnancy Cohort Study (Bumps, Babies and Beyond)
Study abbreviation Triple B
Current principal investigator/s Dr Delyse Hutchinson – Triple B Scientific Director
Professor Richard Mattick – NHMRC Principal Research Fellow 
Current project manager Dr Delyse Hutchinson
Cohort representative (study contact) Dr Delyse Hutchinson
Postal address Triple B Study, School of Psychology, Deakin University, 221 Burwood Hwy Burwood VIC 3128
Phone +613 9246 8778
Email tripleb@deakin.edu.au
Primary Institution

University of New South Wales (UNSW)

Collaborating Institution/s Curtin University; Deakin University; University of Queensland; University of Sydney; Royal Prince Alfred Hospital; Murdoch Childrens Research Institute; Macquarie University
Major funding sources National Health and Medical Research Council
Study website http://ndarc.med.unsw.edu.au/project/triple-b-bumps-babies-and-beyond
Key reference

Hutchinson, D., Wilson, J., Allsop, S., Elliott, E., Najman, J., Burns, L., … & Rossen, L. (2017). Cohort Profile: The Triple B Pregnancy Cohort Study: A longitudinal study of the relationship between alcohol, tobacco and other substance use during pregnancy and the health and well-being of Australian children and families. International journal of epidemiology47(1), 26-27m. 

https://doi.org/10.1093/ije/dyx126

Are data available outside study team? Yes, with formal approval from study investigators only
Study focus Effects of substance use (alcohol, tobacco, illicit drugs) during pregnancy by women and partners on infant development and family functioning.
Sampling frame Women attending antenatal services attached to major hospitals, and specialist drug and alcohol antenatal services, in New South Wales and Western Australia.
Year commenced 2009
Commencement sample 1623
Intergenerational? No 
Imaging No 
Linkage No 
Biosamples? Buccal 
Ethics approvals or requirements? This project only (Specific consent); Future research related to this project (Extended consent)

Waves

Wave Year Age (mean, range) Eligible sample
1  2009-2013 Prenatal – Trimester 1 1,621 families
(1533 mothers general antenatal clinics / 88 mothers specialist drug and alcohol antenatal clinics)
2  2009-2013 Prenatal – Trimester 2 1596 families
(1511 mothers general antenatal clinics / 85 mothers specialist drug and alcohol antenatal clinics)
3  2009-2013 Prenatal – Trimester 3 1579 families
(1498 mothers; 824 partners general antenatal clinics / 81 mothers specialist drug and alcohol antenatal clinics)
4  2009-2013 Birth 1479 families
(1414 mothers; 1453 offspring; 1376 singletons, 37 twin pairs, 1 set of triplets general antenatal clinics / 65 mothers; 65 offspring, all singletons specialist drug and alcohol antenatal clinics)
5  2009-2013  8 weeks of age 1460 families
(1399 mothers; 685 partners*; 1436 infant offspring general antenatal clinics / 61 mothers and infant offspring specialist drug and alcohol antenatal clinics)
*The 8-week follow-up interview for partners was introduced after the pilot study. As such, 8-week data were unavailable for 60
participating partners, as it was not offered.
6  2010-2014 12 months of age ** families
1289 mothers; 711 partners; 1324 infant offspring general antenatal clinics / 48 mothers; 48 infant offspring specialist drug and alcohol antenatal clinics
**In some families, only infants were assessed at 12 months.