Triple B Pregnancy Cohort Study (Bumps, Babies and Beyond)
Synopsis
The Triple B Study: Bumps, Babies and Beyond is an innovative Australian study of approximately 1600 families. The project is a longitudinal pregnancy cohort which examines a wide range of biopsychosocial factors that relate to the health and development of Australian children and families. Importantly, the project has a key focus on examining the impacts of alcohol, tobacco and other drug use in pregnant women and their partners during the prenatal period on infant development and family functioning. The results of this study will inform public health and treatment initiatives that improve the health and well-being of Australian children and families.
Summary
| Study name | The Triple B Pregnancy Cohort Study (Bumps, Babies and Beyond) |
| Study abbreviation | Triple B |
| Current principal investigator/s | Dr Delyse Hutchinson – Triple B Scientific Director Professor Richard Mattick – NHMRC Principal Research Fellow |
| Current project manager | Dr Delyse Hutchinson |
| Cohort representative (study contact) | Dr Delyse Hutchinson |
| Postal address | Triple B Study, School of Psychology, Deakin University, 221 Burwood Hwy Burwood VIC 3128 |
| Phone | +613 9246 8778 |
| tripleb@deakin.edu.au | |
| Primary Institution |
University of New South Wales (UNSW) |
| Collaborating Institution/s | Curtin University; Deakin University; University of Queensland; University of Sydney; Royal Prince Alfred Hospital; Murdoch Childrens Research Institute; Macquarie University |
| Major funding sources | National Health and Medical Research Council |
| Study website | http://ndarc.med.unsw.edu.au/project/triple-b-bumps-babies-and-beyond |
| Key reference |
Hutchinson, D., Wilson, J., Allsop, S., Elliott, E., Najman, J., Burns, L., … & Rossen, L. (2017). Cohort Profile: The Triple B Pregnancy Cohort Study: A longitudinal study of the relationship between alcohol, tobacco and other substance use during pregnancy and the health and well-being of Australian children and families. International journal of epidemiology, 47(1), 26-27m. |
| Are data available outside study team? | Yes, with formal approval from study investigators only |
| Study focus | Effects of substance use (alcohol, tobacco, illicit drugs) during pregnancy by women and partners on infant development and family functioning. |
| Sampling frame | Women attending antenatal services attached to major hospitals, and specialist drug and alcohol antenatal services, in New South Wales and Western Australia. |
| Year commenced | 2009 |
| Commencement sample | 1623 |
| Intergenerational? | No |
| Imaging | No |
| Linkage | No |
| Biosamples? | Buccal |
| Ethics approvals or requirements? | This project only (Specific consent); Future research related to this project (Extended consent) |
Waves
| Wave | Year | Age (mean, range) | Eligible sample |
|---|---|---|---|
| 1 | 2009-2013 | Prenatal – Trimester 1 | 1,621 families (1533 mothers general antenatal clinics / 88 mothers specialist drug and alcohol antenatal clinics) |
| 2 | 2009-2013 | Prenatal – Trimester 2 | 1596 families (1511 mothers general antenatal clinics / 85 mothers specialist drug and alcohol antenatal clinics) |
| 3 | 2009-2013 | Prenatal – Trimester 3 | 1579 families (1498 mothers; 824 partners general antenatal clinics / 81 mothers specialist drug and alcohol antenatal clinics) |
| 4 | 2009-2013 | Birth | 1479 families (1414 mothers; 1453 offspring; 1376 singletons, 37 twin pairs, 1 set of triplets general antenatal clinics / 65 mothers; 65 offspring, all singletons specialist drug and alcohol antenatal clinics) |
| 5 | 2009-2013 | 8 weeks of age | 1460 families (1399 mothers; 685 partners*; 1436 infant offspring general antenatal clinics / 61 mothers and infant offspring specialist drug and alcohol antenatal clinics) *The 8-week follow-up interview for partners was introduced after the pilot study. As such, 8-week data were unavailable for 60 participating partners, as it was not offered. |
| 6 | 2010-2014 | 12 months of age | ** families 1289 mothers; 711 partners; 1324 infant offspring general antenatal clinics / 48 mothers; 48 infant offspring specialist drug and alcohol antenatal clinics **In some families, only infants were assessed at 12 months. |